Biotechnologies
Many natural molecules boast two major qualities: efficacy and safety. However, some active ingredients have low probabilities of being absorbed by the human body, if used as nature provides them. As a result, they would achieve low bioavailability and consequently be poorly effective. Nonetheless there is the possibility of enhancing these molecules with biological technologies that do not alter the structure of the active ingredients to which they are applied, improving their final efficacy.
EIDON Salus has studied and developed specific biotechnologies for the Medical Devices and Nutraceuticals in its catalog, and has patented some of them.
Hydrolyzed Hyaluronic Acid
The term hydrolyzed hyaluronic acid refers to hyaluronic acid that has been “fragmented” through hydrolysis: a process that makes it extremely bioavailable as it can be absorbed sublingually and is permeable to the intestinal barrier.
Two of EIDON Salus’ products containing hyaluronic acid, CARTIAL D and OSIDRA, include hydrolyzed hyaluronic acid in their composition.
OSIDRA combines two different molecular weights of hyaluronic acid. Moreover sophisticated laboratory processing leads to an ideal rheology, making the product fluid and easily dispensed from a controlled spray.
CARTIAL D and OSIDRA are the first products based on hyaluronic acid, effective for systemic use: they can be taken orally.
Chitosan Complexes
Chitosan is a natural polymer gained from the alkaline deacetylation of chitin. It can be found in the exoskeletons of crustaceans, insects, and certain types of fungi. Chitosan has significant applications in various fields: pharmaceuticals as a carrier for controlled medicines release, owing to its unique properties such as biocompatibility, biodegradability, non-toxicity, mucoadhesion and the ability to enhance the paracellular transport of medical drug. Chitosan has been recently proposed as a vehicle for controlled medicine release through mucosal membranes. Therefore the final bioavailability of active ingredients significantly increases.
EIDON salus uses this biotechnology for:
BIOST: Glucosam-CH and Bosw-CH, Glucosamine and Boswellia Serrata complexed in chitosan microspheres.
(Drug dev Ind Pharm.2012Jan;38:104-10 doi:10.3109/03639045.2011.592531.Epub2001Jul20.)
